WebOct 27, 2016 · Chitlac was shown to produce positive biological effects on chondrocytes and human osteosarcoma cell lines through Galectin-mediated interactions . Chitlac was … WebAlginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. Numerous studies indicate that alginate applied in …

Cell-protection mechanism through autophagy in HGFs/

WebAfter 24 h thermosets coated with Chitlac as well as those coated with Chitlac-nAg exerted a minimal cytotoxic effect on HGFs, while after 48 h LDH release raised up to 20 %. Moreover the presence of S. mitis reduced this release mainly when HGFs adhered to Chitlac-nAg coated thermosets. The reduced secretion of collagen type I was significant ... WebIn particular, Chitlac (Ch) is a compound obtained by the modification of chitosan with lactitol moieties , in which the oligosaccharide pendant groups alter its solubility at physiological pH. The physico-chemical and biological properties of Ch are already reported in the literature [ 17 ]. cyretha barbee

Synergistic Effects in Semidilute Mixed Solutions of Alginate and ...

WebSep 30, 2013 · Chitlac is a biocompatible modified polysaccharide composed of a chitosan backbone to which lactitol moieties have been chemically inserted via a reductive N … WebOct 22, 2014 · Chitlac (CAS registry number 85941-43-1) was prepared according to the procedure reported by Donati et al [ 20 ]. To produce the coating solution, the … WebBy containing a gel-forming polyanion (alginate, e.g., with Ca 2+ ions) and a bioactive polycation (chitlac, bearing a β-linked d -galactose), the present system can be regarded as a first step toward the development of biologically active scaffold from polysaccharide mixtures. † University of Trieste. * binary waves de lab au 2008