Dynamo mapping vector field of single cells
WebDynamo: Mapping Transcriptomic Vector Fields of Single Cells. Inclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector … WebDynamo: Mapping Transcriptomic Vector Fields of Single Cells. Inclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector field reconstruction, potential landscape mapping, …
Dynamo mapping vector field of single cells
Did you know?
WebJul 9, 2024 · Here, we introduce dynamo, an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity … WebFeb 2, 2024 · Our analytical framework, dynamo, consists of four integral stages: 1) estimation of genome-wide kinetic rate constants and velocity vectors, 2) reconstruction of single-cell vector field functions with the resultant cell state and velocity samples, 3) in-depth analyses leveraging various differential geometry analyses, and 4) predictions of ...
WebFeb 1, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, howev WebFeb 1, 2024 · Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires ...
Web•Vector fields reveal the timing and mechanisms of human hematopoiesis •Dynamo allows cell-state transition path and in silico perturbation predictions . Summary. Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. WebMar 31, 2024 · Wagner, D. E. et al. Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo. Science 360, ... Qiu, X. et al. Mapping vector field of single cells.
http://dynamo-readthedocs.readthedocs.io/
WebLeveraging the least-action-path method, dynamo accurately predicts drivers of numerous hematopoietic transitions. Finally, in silico perturbations predict cell-fate diversions … chiltern choirWebInclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector field reconstruction and differential geometry analyses - GitHub - KBRI-Biology-Experiment-Comput... grade 4 teacher salary in south africaWebQiu X, Zhang Y, Yang D, et al. Mapping vector field of single cells[J]. Biorxiv, 2024. 这个 RNA velocity and beyond 系列之后大概会写 Theory 部分 ，主要介绍 model detail，怎么 estimate parameter等，最后写 beyond 的部分，也就是dynamo 的内容。 欢迎大家在评论区讨论（虽然我估计没什么人看hhhh） grade 4 term 3 maths trackerWebAug 22, 2024 · Dynamo: Mapping Transcriptomic Vector Fields of Single Cells. Inclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector field reconstruction, potential landscape mapping, differential geometry analyses, and most probably paths / in silico perturbation predictions. chiltern churchWebJul 9, 2024 · Here, we introduce dynamo , an analytical framework that reconciles intrinsic splicing and labeling kinetics to estimate absolute RNA velocities, reconstructs velocity vector fields that predict future cell fates, and finally employs differential geometry analyses to elucidate the underlying regulatory networks. grade 4 term 1 mathematics assignmentchiltern church suttonWebFeb 18, 2024 · To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that leverages estimates of unprocessed transcript and protein abundances to extrapolate cell states. ... Wang L, Yuan R, et al. Mapping Vector Field of Single Cells. Biorxiv. 2024;9:696724. Google Scholar … chiltern church antiques