WebA prominent example is polytheonamide A, which exhibits numerous post-translational modifications, some of which were unknown in ribosomal peptides until recently. Among these post-translational modifications, C-methylations have been proposed to be catalyzed by two putative radical S-adenosylmethionine (rSAM) enzymes, PoyB and PoyC. WebPolytheonamide B (1) is an ion-channel forming natural peptide with a d, l-alternating 48 amino acid sequence, which is an exceedingly potent cytotoxin.We recently designed and …
Design, Synthesis and Functional Analysis of Dansylated …
WebMar 21, 2016 · Structure and dynamics of solvent molecules inside the polytheonamide B channel in different environments: a molecular dynamics study. Physical Chemistry … WebFeb 21, 2010 · Polytheonamide B is by far the largest non-ribosomal peptide known at present, and displays extraordinary cytotoxicity (EC50 = 68 pg ml−1, mouse leukaemia … cipher\\u0027s oh
Rectified Proton Grotthuss Conduction Across a Long Water-Wire …
WebThe easiest way is to use a reference manager: The citation style is built in and you can choose it in Settings > Citation Style or Paperpile > Citation Style in Google Docs. The style is either built in or you can download a CSL file that is supported by most references management programs. BibTeX syles are usually part of a LaTeX template. WebT1 - Polytheonamide biosynthesis showcasing the metabolic potential of sponge-associated uncultivated 'Entotheonella' bacteria. AU - Freeman, Michael F. AU - Vagstad, Anna L. AU - Piel, Jörn. N1 - Funding Information: We would like to thank Eike Peters for providing the ‘Entotheonella’ image depicted in Figure 3 . WebApr 1, 2016 · The leader sequence for the polytheonamide precursor PoyA bears homology to the alpha subunit of nitrile hydratases, yet with the conserved metal-chelating residues … dialysis clinic inc elko nv